Dr. Alexander Klimovich

2020

Dynamic interactions within the host-associated microbiota cause tumor formation in the basal metazoan Hydra.

Rathje K, Mortzfeld B, Hoeppner MP, Taubenheim J, Bosch TCG, Klimovich A (2020) PLOS Pathogen. 16(3):e1008375. doi: 10.1371/journal.ppat.1008375

2019

FeaturedTemperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways

Mortzfeld BM*, Taubenheim J*, Klimovich AV, Fraune S, Rosenstiel P, Bosch TCG (2019) Nature Communications 10, 3257. doi: 10.1038/s41467-019-11136-6

FeaturedTransgenesis in Hydra to characterize gene function and visualize cell behaviour.

Klimovich A, Wittlieb J, Bosch TCG (2019) Nat. Protoc., 1-24. doi: 10.1038/s41596-019-0173-3

2018

Non-senescent Hydra tolerates severe disturbances in the nuclear lamina.

Klimovich A, Rehm A, Wittlieb J, Herbst EM, Benavente R, Bosch TCG (2018); Aging (Albany NY) 10(5):951-972. doi: 10.18632/aging.101440

Rethinking the Role of the Nervous System: Lessons From the Hydra Holobiont.

Klimovich AV, Bosch TCG (2018); Bioessays 40(9):e1800060. doi: 10.1002/bies.201800060

Stem cell transcription factor FoxO controls microbiome resilience in Hydra.

Mortzfeld B M, Taubenheim J,Fraune S, Klimovich A V, Bosch T C G (2018); Front Microbiol., doi: 10.3389/fmicb.2018.00629

2017

Spontaneous body contractions are modulated by the microbiome of Hydra.

Murillo-Rincon A P, Klimovich A, Pemöller E, Taubenheim J, Mortzfeld B, Augustin R, Bosch T C G (2017); Scientific Reports, 7(15937). doi:10.1038/s41598-017-16191-x