Prof. Dr. Sebastian Fraune
Institution
Contact
Vita
Education/Training
2005 – 2009
Dissertation at the Christian-Albrechts University of Kiel, Zoological Institute, (supervised by Prof. Dr. Dr. h.c. Bosch), Title: Towards understanding a holobiont: Host-microbe interaction in Hydra; “summa cum laude”
1999 – 2005
Diploma in Biology (Microbiology, Limnology, Toxicology), Christian-Albrechts University of Kiel, Germany
Research Experience/Academic Appointments
Since 2019
Professor for Zoology and Organismic Interactions (W2), Heinrich-Heine University Düsseldorf
2013 – 2018
Independent junior research group leader at the Christian-Albrechts University of Kiel, Zoological Institute
2009 – 2013
Postdoctoral Fellow, Zoological Institute, Christian-Albrechts-University of Kiel, Germany, group of Prof. Dr. Dr. h.c. Thomas Bosch
Important Scientific Prizes/Functions
Since 2013
Editorial service for scientific journal: Frontiers in Microbial Symbiosis – Associate Editor
Since 2012
Referee service for scientific journals: Nature Communications, PNAS, ISMEJ, eLife, Environmental Microbiology, BMC Genomics, PLoS ONE, Marine Biology, Bioessays, Frontiers in Microbial Symbiosis
2011
Awards: Poster Prize, Gordon Research Conference Antimicrobial Peptides in Innate Immunity – New Insights on an Ancient System
2008
Travel grant to participate at the 2nd ASM Conference on Beneficial Microbes, San Diego (USA)
Research
Publications
2019
FeaturedComparative analysis of amplicon and metagenomic sequencing methods reveals key features in the evolution of animal metaorganisms
Rausch P, Rühlemann M, Hermes BM, Doms S, Dagan T, Dierking K, Domin H, Fraune S, von Frieling J, Hentschel U, Heinsen F-A, Höppner M, Jahn MT, Jaspers C, Kissoyan KAB, Langfeldt D, Rehman A, Reusch TBH, Roeder T, Schmitz RA, Schulenburg H, Soluch R, Sommer F, Stukenbrock E, Weiland-Bräuer N, Rosenstiel P, Franke A, Bosch T, Baines JF (2019) Microbiome, doi: 10.1186/s40168-019-0743-1
FeaturedTemperature and insulin signaling regulate body size in Hydra by the Wnt and TGF-beta pathways
Mortzfeld BM*, Taubenheim J*, Klimovich AV, Fraune S, Rosenstiel P, Bosch TCG (2019) Nature Communications 10, 3257. doi: 10.1038/s41467-019-11136-6
FeaturedNeutrality in the metaorganism
Sieber M, Pita L, Weiland-Bräuer N, Dirksen P, Wang J, Mortzfeld B, Franzenburg S, Schmitz RA, Baines JF, Fraune S, Hentschel U, Schulenburg H, Bosch TCG, Traulsen A (2019) PLoS Biol., DOI: 10.1371/journal.pbio.3000298
Bdellovibrio and like organisms are predictors of microbiome diversity across diverse host groups.
Johnke J, Fraune S, Bosch TCG, Hentschel U, Schulenburg H (2019) Microbial Ecology DOI: 10.1007/s00248-019-01395-7
Resolving structure and function of metaorganisms through a holistic framework 2 combining reductionist and integrative approaches
Jaspers C, Fraune S, Consortium of Australian Academy of Science Boden Research Conference Participants, Arnold AE, Miller DJ, Bosch TCG, Voolstra CR (2019) Zoology. doi: 10.1016/j.zool.2019.02.007
2018
Metabolic co-dependence drives the evolutionarily ancient Hydra-Chlorella symbiosis.
Hamada M, Schröder K, Bathia J, Kürn U, Fraune S, Khalturina M, Khalturin K, Shinzato C, Satoh N, Bosch TC (2018); Elife 7. pii: e35122. doi: 10.7554/eLife.35122
Carrying capacity and colonization dynamics of Curvibacter in the Hydra host habitat
Wein T, Dagan T, Fraune S, Bosch TCG, Reusch TBH and Hülter NF (2018) Front. Microbiol., https://doi.org/10.3389/fmicb.2018.00443
Predicted bacterial interactions affect in vivo microbial colonization dynamics in Nematostella
Domin H, Zurita-Gutiérrez Y, Scotti M, Buttlar J, Hentschel Humeida U and Fraune S (2018) Frontiers in Microbiology 9, 728, https://doi.org/10.3389/fmicb.2018.00728
Stem cell transcription factor FoxO controls microbiome resilience in Hydra.
Mortzfeld B M, Taubenheim J,Fraune S, Klimovich A V, Bosch T C G (2018); Front Microbiol., doi: 10.3389/fmicb.2018.00629
Metaorganisms in extreme environments: do microbes play a role in organismal adaptation?
Bang C, Dagan T, Deines P, Dubilier N, Duschl W J, Fraune S, Hentschel U, Hirt H, Hülter N, Lachnit T, Picazo D, Galan P L, Pogoreutz C, Rädecker N, Saad M M, Schmitz R A, Schulenburg H, Voolstra C R, Weiland-Bräuer N, Ziegler M, Bosch T C G (2018); Zoology, doi: 10.1016/j.zool.2018.02.004
2017
Temperate phages as self-replicating weapons in bacterial competition.
Li XY, Lachnit T, Fraune S, Bosch T C G, Traulsen A, Sieber M (2017); J R Soc Interface, 14(137). doi: 10.1098/rsif.2017.0563
FeaturedA secreted antibacterial neuropeptide shapes the microbiome of Hydra.
Augustin R, Schröder K, Murillo Rincón A P, Fraune S, Anton-Erxleben F, Herbst E M, Wittlieb J, Schwentner M, Grötzinger J, Wassenaar T M, Bosch T C G (2017); Nat Commun., 8(1):698. doi: 10.1038/s41467-017-00625-1
2016
Emerging Sponge Models of Animal-Microbe Symbioses.
Pita L, Fraune S, Hentschel U (2016); Front Microbiol., 7:2102. doi: 10.3389/fmicb.2016.02102
Using Nematostella vectensis to Study the Interactions between Genome, Epigenome, and Bacteria in a Changing Environment.
Fraune S, Forêt S, Reitzel A M (2016); Front. Mar. Sci., 3:148. doi: 10.3389/fmars.2016.00148